How blood stem cells maintain their lifelong potential for self-renewal

(German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ)) A characteristic feature of all stem cells is their ability to self-renew. But how is this potential maintained throughout life? Scientists at the German Cancer Research Center (DKFZ) and the Heidelberg Institute for Stem Cell Technology and Experimental Medicine* (HI-STEM) have now discovered in mice that cells in the so-called "stem cell niche" are responsible for this,